Scottish teams Rangers and Celtic, along with other leading clubs from the Netherlands, Portugal, Belgium and Scandinavia, are working on plans to form a new 16-team competition.
"We have major concerns with what they are proposing," Mike Lee, UEFA's director of communications, said.
He said UEFA officials had heard submissions from the clubs concerned but rejected suggestions that any decision on the proposed league would be taken at the UEFA executive committee meeting on October 4 and 5 at Nyon in Switzerland.
"It is highly unlikely. We made it clear we would reflect their ideas and concerns to the next meeting of the UEFA executive committee.
"That is a normal scheduled meeting. It has not been especially convened to discuss the concerns of these clubs."
Under the plans the new league would include four sides each from the Netherlands and Portugal, three from Scotland, two from Belgium and three shared by Norway, Sweden and Denmark.
Qualification would be on merit, with the clubs finishing in the top three in their domestic leagues next season winning promotion to the European league.
With a potential television audience of 60 million the 16 clubs believe they can improve their revenue which is currently restricted by modest national TV deals.
Rangers and Celtic have already been given the backing of the Scottish Premier League (SPL) to pursue the creation of the new league.
Reuters
European soccer's ruling body UEFA has "major concerns" over proposals by a number of clubs to abandon their national championships and set up their own league together.
